Thursday 25 November 2010

Chemotherapy Cancer Breakthrough?

Chemotherapy usually relies on cells to take in drugs by diffusion across the cell membrane, but sometimes this doesn't work effectively as some cells just pump the drug molecules back out.
But researchers at the University of Ulm have found that cells absorb the drugs more readily if they are exposed to pulsed red light. The wavelength of this light  decreases water density and pushes water out of the cell. Then, when the red light is taken away, the cell return to it's previous high density state and water, and any other molecules (including drugs) from the surrounding area are drawn into the cell by simple diffusion.
This process was tested for one minute on human cervical cancer cells surrounded by common anti-cancer drugs. Even though it was only a short period of exposure to the red light, it was enough to kill off 70% of the cancer cells. When compared with a control experiment, in which cancer cells weren't exposed to red light, only 31% of cancer cells were killed.
This research will hopefully help to produce more effective cancer treatments

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